Purpose: Clinical educators often look for retroactive clues when a student ÒfailsÓ a clinical education experience.Ê The purpose of this study is to identify relationships between success in the didactic portion of the curriculum with success or failure on clinical education. A secondary aim is to determine if any didactic classes are predictive of failure in clinical education so educators can be more proactive with students who are at risk.Methods/Description: This retrospective study used de-identified academic course grades from 295 doctor of physical therapy students enrolled in a large urban university over a 3-year years. From this cohort, 12 students (4%) failed a clinical. Amongst students that failed a clinical, the mean GPA was 3.21 (4.0 scale), whereas students who passed all clinicals had a 3.45. Other student characteristics were not determined since the data was de-identified. All didactic course grades from the professional phase of the curriculum were included as independent variables, as well as selected grades from the pre-professional phase. Comparison of the mean grades between the two groups (students who either did or did not fail a clinical) were conducted using t-test, one way ANOVA and Tukey-Kramer post-testing.Results/Outcomes: 26 variables were found to have statistically significant differences in mean grades when compared between students that failed a clinical compared to those that did not (p-value: 0.05). In the pre-professional phase of the curriculum, students who failed a clinical had significantly lower mean grades in Anatomy & Physiology 2 Lab (-0.580), Physics for Life Sciences lecture and lab (-0.514) and Developmental Psychology (-0.508).Ê In the professional phase of the curriculum, the classes with the largest difference between the groups were Neurological Management 2 Lab (-0.540), Pathology (-0.506) and Gross Anatomy Lab (-0.451).Conclusions/Relevance to the conference theme: Shaping the Future of Physical Therapy Education: Results of the analysis demonstrate specific classes have predictive value in whether or not a student will go on to successfully complete all of their clinicals. 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