Developing effective collaborations between academic institutions and health system organizations is crucial for clinical and health services research success. Real-world challenges and barriers exist in cultivating these relationships. Yet, these partnerships provide unique opportunities for clinician engagement in advancing physical therapy research. This session will highlight the opportunities and challenges of developing these types of research collaborations from unique stakeholder perspectives. Three rehabilitation scientists at different stages in their research careers will describe their experiences and discuss facilitators, barriers, and lessons learned along their early career path towards high-impact collaborative research. Clinician, clinical research coordinator, and administrator perspectives will be shared to provide viewpoints and experiences from additional stakeholders. Discussion will be encouraged through a moderated question and answer session facilitated by a leader in physical therapy research.